Lan kwai fong
A few blocks uphill from Central MTR, this is Hong Kong's traditional expat hangout. Drinks are fairly pricy with even your basic beer costing $50 and up, but there are dozens of bars for you to chose from plus a 7-11 store which sells beer and mixed drinks for much lower prices than the bars - and the staff will even open the bottles for you. There is always something going on in The Fong, be it street festivals during the Halloween and New Year's celebrations or the Beer and Food Festivals that pop up in the summer. If you want good food, a party atmosphere, or just to people watch, make sure Lan Kwai Fong is part of your trip.
Soho
The Globe
Excellent beer pub, also has good menu aimed at western taste buds. It is also one of the few places that has Typhoon T8 on tap, a locally produced cask ale.